Otsoniterapiaa Kiinassa

 

Miika Sallinen 8.1.2011

 

Kun vuosina 2003-2004 kirjoitin kirjaani Otsoni- ja vetyperoksidihoidot, pyrin sitä varten etsimään kaiken saatavilla olevan informaation otsoniterapioista. Kattavasta työstä huolimatta en löytänyt yhtään Kiinassa tehtyä tutkimusta. Vasta aivan viime vuosina olen onnistunut löytämään niitä useitakin. Tämä ei ole ihme, sillä otsoniterapia on rantautunut Kiinaan vasta viimeisen vuosikymmenen aikana. Uutuudestaan huolimatta hoitomuodon leviäminen Kiinassa on ollut tehokasta verrattuna moneen muuhun maahan. Tähän on useita syitä. Kiinassa on perinteisesti suhtauduttu positiivisesti erilaisiin hoitomuotoihin, eikä länsimainen koululääketiede ole ollut siellä ainoa oikea totuus. Sosialistisena maana lääkeyhtiöillä on Kiinassa varsin vähän merkitystä terveydenhuollon kehittämiseen. Lisäksi Kiina on huomattavasta talouskasvusta johtuen vaurastunut paljon, joten maalla huomattavat resurssit tehdä uudenlaista tutkimusta.

Päätin tällä kertaa kirjoittaa lyhyen katsauksen Kiinassa suoritetusta otsoniterapiasta. Alussa toimin toimin kääntäjänä, sillä uusimmassa International Journal of Ozone Therapy -lehdessä oli lyhyt artikkeli Kiinassa suoritetusta otsoniterapiasta. Artikkelin on kirjoittanut professori Xiaofeng He, ja se on käännettynä seuraavassa:

 

on kulunut kymmenen vuotta siitä, kun otsoniterapiaa ensi kerran suoritettiin Kiinassa vuonna 2000. Viime vuosikymmenellä otsoniterapian alueella on tapahtunut huomattavia edistysaskelia. Aluksi sitä käytettiin vain lantiorangan välilevytyrän hoidossa, mutta nykyään myös lukuisten kiputilojen, osteoartriitin, gynekologisten tulehdusten, haavojen, viruksen aiheuttaman hepatiitin, aivoinfarktin jne. hoidossa. Tällä hetkellä sadat sairaalat ovat jo perustaneet otsoniterapiaohjelman, ja keskeneräisten tilastojen mukaan, sadat tuhannet potilaat saavat tätä terapiaa vuosittain. Potilaita, joilla on kaula- tai lantiorangan välilevyntyrä, hoidetaan vuosittain yli 50 000, ja yli 80 % heistä erinomaisin tuloksin.

Kiinassa HBV:n [B-hepatiitti] esiintyvyys on hyvin suuri, ja otsoni-autohemoterapian teho vastaa suun kautta otettuja antiviraalisia lääkkeitä. Niinpä potilaille, joihin lääkkeet eivät tehoa, otsoni-autohemoterapia on paras vaihtoehto. Tällä hetkellä monissa sairaaloissa tehdään kliinistä tutkimusta otsoniterapian käytöstä aivoinfarktin hoidossa, ja tällä alueella on tapahtunut nopeaa kehitystä.

Alustavan tutkimuksen tulokset osoittavat, että otsoniterapia voi vähentää aivojen turvotusta ja edistää aivokudoksen korjautumista, mikä on ollut uusi tutkimuskohde viimeisen kahden vuoden aikana. Otsoniterapian käyttö kasvainten hoidossa on yhä lapsenkengissä, mutta silläkin alalla on muutamia hyviä merkkejä. Syyskuussa 2008 perustettiin Kiinan otsoniterapiajärjestö, jossa merkittävä tukena oli professori JiaXiang Ni, maailman kivunhoitojärjestön Kiinan osaston presidentti. Järjestön johtajana toimii professori Xiaofeng He, ja sen hallintoa vahvistavat maksaspesialisti professori Yabing Guo, ortopedian asiantuntija professori Bin Yu ja neurologian ekspertti Kairun Peng.

Helmikuussa 2009 ilmestyi Xiaofeng Hen toimittama kirja "Otsoniterapian kliiniset sovellutukset". Se on ensimmäinen ammattilaisille tarkoitettu otsoniterapiaa käsittelevä teos Kiinassa ja siihen on koottu viimeisin tutkimus useilta osa-alueilta. Ensimmäinen ja toinen vuosittainen konferenssi on menestyksellisesti pidetty järjestön perustamisen jälkeen. Molemmilla kerroilla osallistujia oli yli 300 ja jäseniä 288. Noin 30 sairaalalle tai lääkäriasemalle on myönnetty "Esimerkillinen otsoniterapiayksikkö" tai "Standardoitu otsoniterapiayksikkö" sertifikaatti. Samanaikaisesti, saksalaisen HUMARIES-yhtiön taloudellisella tuella, NANFANG HOSPITAL-HUMARES-niminen otsoniterapian koulutuskeskus on perustettu erikoistumaan ja järjestelmällisesti kouluttamaan lääkäreitä, jotka ovat vielä noviiseja otsoniterapian alalla. Harjoituskurssit sisältävät otsoniterapiaa välilevyn pullistumiin, maksan tauteihin, aivoverenkiertohäiriöihin, osteoartriittiin ja käytäntöön koe-eläinten kanssa.

 

Me uskomme että lähitulevaisuudessa muiden hoitojen tavoin myös otsoniterapiaoista hyötyy yhä useampi potilas.

Jos nyt oikein haluaa saivarrella, niin todellisuudessa kiinassa on käytetty otsonia ainakin hiukan ennen vuotta 2000. Xiaofeng He kirjoitti Rivista Italiana Di Ossigeno-Ozonoterapia -lehdessä vuonna 2003, kuinka kiinalaiset tutkijat aloittivat yhteistyön italialaisen Osperdale Bellarian sairaalan kanssa vuonna 2000. Siitä alkoi juuri selkäongelmia koskeva otsonitutkimus Kiinassa. Muulla osa-alueella tutkimusta oli tehty ainakin hieman aiemmin, sillä samana vuonna ilmestyi ensimmäinen palovammojen hoitoa koskeva otsonitutkimus Kiinasta. Vaikka en olekaan kieliongelmien vuoksi voinut tutustua kyseiseen tutkimukseen, se lienee kuitenkin suoritettu jo 1990-luvun puolella.

Jotta lukijalle jäisi jonkinlainen käsitys Kiinassa viime vuosina suoritetusta otsonitutkimuksesta, liitän tuohon loppuun viitteet niistä Kiinassa tehdyistä tutkimuksista, joista itse olen tietoinen. Olen löytänyt ne useista eri tietokannoista kuten PubMed:sta ja ennen kaikkea CNKI:sta (China National Knowledge Infrastructure) sekä CAOD:sta (China Asia on Demand). Lisäksi joitakin viitteitä on löytynyt italiaisen Centauron sivuilta. Centauro kustantaa useita tiedejulkaisuja, joissa on julkaistu otsoniterapiaan liittyviä tutkimuksia. Tärkeimpänä niistä International Journal of Ozone Therapy. Vaikka olen lähes poikkeuksetta tutustunut kaikkeen viittaamaani alkuperäismateriaaliin, tällä kertaa tunnustan, että oheisen listan tutkimuksista olen lukenut pääosin vain tiivistelmät. CNKI:n julkaisuihin ei ole vapaata pääsyä, ja koska valtaosa niistä on kirjoitettu Kiinaksi, en ole ajatellut maksaa niiden lukemisesta. Se kun ei onnistuisi muutenkaan kuin korkeintaan kääntäjän avulla.

Oheisen listan kokoaminen oli työläs yllätys. Haeskelen tutkimusmateriaalia eri tietokannoista ja internethaulla muutamia kertoja vuodessa. Toistaiseksi olin sivuuttanut kiinalaisten tutkimukset, mikäli ne oli kirjoitettu kiinaksi. Yleensä esimerkiksi otsikot oli käännetty englanniksi, joten satunnaisesti niihin törmäsin, ja olin edes jollain tavoin tietoinen Kiinan tilanteesta. Kun sitten etsin tutkimusviitteitä kiinalaisten omista tietokannoista, tutkimusten määrä yllätti minut täysin. Niitä ei ollutkaan noin 20 kappaletta, vaan kokonaismäärä tämän kirjoituksen julkaisun aikana oli kasvanut 219:aan, mikä 12 koon fontilla vastasi lähes 16 sivua viitteitä. Koska kaiken muun ohessa olen kasaamassa tietokantaa otsoniterapioista Zotero-tutkimustyökaluun, päätin lisätä nuo artikkelit siihen saman tien. Sitä mukaa kun lisäsin artikkeleita, löytyi monta uutta. Yhden illan puuhasteluksi tarkoitettu venyi parin viikon työksi.

Tuo kiinalaisten artikkelien kasaaminen ja liittäminen ne Zotero-tietokantaan oli myös opettavainen kokemus. Siinä kun tuli samalla selvitettyä, millaista tutkimusta Kiinassa oikein on tehty. Oheisessa professori Hen kirjoituksessa kävi ilmi, miten Kiinassa on tutkittu erityisesti välilevyongelmien hoitoa otsonilla. Kaikista löytämistäni tutkimuksista yli puolet olikin erilaisiin selkäongelmiin liittyviä kliinisiä tutkimuksia. Kaikkiaan niitä löytyi 125 kappaletta, mikä tarkoittaa, että aihetta on tutkittu Kiinassa jo kutakuinkin yhtä paljon kuin Italiassa, missä hoidot alun perin kehitettiin.

Selkäkipujen lisäksi Kiinassa on tutkittu myös muun tyyppisiä kipuja. Polven nivelrikosta löysin kolme tutkimusta. Kolmessa muussa oli tutkittu erilaisia hermosärkyjä eli neuralgioita, joista kahdessa aiheuttajana oli on ollut Herpes zoster -infektio. Tenniskyynärpään hoidosta löytyi yksi artikkeli. Lisäksi yksi kliininen tutkimus käsitteli kivunhoitoa yleisesti.

Xiaofeng He Mainitsi myös B-hepatiitin tutkimisesta. Tästä aiheesta löysin seitsemän Kiinassa tehtyä tutkimusta, jotka kaikki olivat suhteellisen suppeita vaihdellen tapauskertomuksista korkeintaan muutaman kymmenen potilaan tutkimuksiin. Huomattavasti laajempaa tutkimus on ollut erilaisten naistentautien alalla. Siltä alalta löytyi kaikkiaan 16 viitettä. Kaikkein tutkituin aihe oli Candida-hiivan liikakasvu, eli tavallisemmin emättimen hiiva. Koska Candida albicans -hiivasieni kuuluu elimistön normaaliin mikrobistoon, kyseisen oireen diagnoosi on vaikeaa, eikä taudin olemassaoloakaan yleisesti tunnusteta. Ehkäpä juuri siksi länsimaista ei ole juurikaan ilmestynyt aihetta käsitteleviä otsoniterapiatutkimuksia, mutta nyt kiinalaiset ovat merkittävästi muuttaneet tilannetta. Valitettavasti heidän tutkimuksensa tästä aiheesta on julkaistu ainoastaan kiinaksi. Tutkimustiivistelmät on onneksi saatavilla myös englanniksi, ja niistä selviää, että tulokset ovat olleet poikkeuksetta erittäin hyviä.

Haavanhoito kuuluu alueisiin, jolla otsoniterapiaa on tutkittu runsaasti. Kiinasta onnistuin löytämään viisi tutkimusta. Palovammojen hoidosta tutkimuksia löytyi kaksi kappaletta. Suolistosairauksista oli yksittäiset kliiniset tutkimukset suoritettu ärtyneen suolen oireyhtymästä ja haavaisesta paksusuolentulehduksesta eli colitis ulcerosasta. Näiden lisäksi löytyi muutamia suppeita tutkimuksia harvinaisemmista taudeista ja onpa yksi tutkimus hammaslääketieteenkin alalta karieksen hoidosta.

Professori He mainitsi artikkelissaan sekä syövänhoidosta että aivoinfarktin hoidosta otsonilla. Jälkimmäisestä en löytänyt julkaistua tietoa, mikä ei toisaalta ole yllättävää huomioiden tutkimusten olevan vasta alkuvaiheessa. Syövänhoidosta löytyi kolme tutkimusta, joista kaksi käsitteli imusolmukesyöpiä ja yksi kurkunpään syöpää.

Kliinisten tutkimusten lisäksi Kiinassa on tehty suuri määrä laboratorio- ja eläinkokeita. Iso osa niistä liittyy kliinisten tutkimusten tavoin välilevyongelmiin, mutta myös moneen muuhun osa-alueeseen. Kaikkiaan tällaisia artikkeleita löysin 39 kappaletta. Lisäksi löytyi kolme kappaletta katsaustyyppisiä artikkeleita, joista yksi ole ylempänä lainattu suppeahko katsaus Kiinan tilanteesta. Näiden lisäksi oli vielä yksi artikkeli, joka muista poiketen ei ollut niinkään tervetullut, mutta rehellisyyden nimissä siitäkin on mainittava. Otsoniterapia ei Kiinassakaan ole ollut täysin riskitöntä, vaikka onnettomuudet ovatkin äärimmäisen harvinaisia. Eräässä artikkelissa oli kuvaus välilevytulehduksesta, joka syntyi mitä ilmeisimmin otsoni-injektion yhteydessä levinneestä Streptococcus bovis -infektiosta. Tässäkin tapauksessa potilas onneksi pääosin toipui leikkauksen jälkeen muutamassa kuukaudessa.

 

Etsiessäni artikkeleita ja lisäillessäni Zotero-tietokantaan, panin luonnollisesti merkille, miten tutkimusten määrä on noussut hurjasti aivan viime vuosien aikana. Tein artikkelien ilmestymisestä oheisen kaavion, joka kuvaa löytämieni artikkelien määrää niiden ilmestymisvuoden mukaan. Kuten huomataan, tutkimukset Kiinassa kasvoivat hurjasti vuodesta 2000 vuoteen 2008. Sen jälkeen kasvu on epäilemättä edelleen ollut hurjaa, mutta vuoden 2009 artikkelit ovat vielä osittain indeksoimatta ja vuoden 2010 osalta vielä varsin suurelta osin indeksoimatta eri tietokantoihin. Oheisen kaavion perusteella ei siis pidä tehdä johtopäätöstä, että tutkimus Kiinassa olisi kääntynyt laskuun vuoden 2008 jälkeen. Todellisuudessa tilanne on varmasti päinvastainen ja uusia tutkimuksia tehdään nopeammalla tahdilla kuin koskaan ennen.

 

Kaavio 1. Indeksoimieni kiinalaisten otsoniterapiajulkaisujen määrä niiden ilmestymisvuoden mukaan.

 

Ilmestyneiden tutkimusten määrä on jo nyt varsin suuri. Sen perusteella Kiina kuuluu ehdottomasti merkittävimpien otsoniterapiamaiden joukkoon. Eniten tutkimuksia on toki edelleen tehty Venäjällä ja merkittävimpiin länsimaisiin tiedejulkaisuihin ovat eniten tuloksiaan tuottaneet italialaiset tutkijat. Lisäksi pitäisin Kuubaa ja Saksaa edelleen Kiinaa merkittävämpänä otsonitutkimusmaana, vaikka tutkimusten kokonaismäärässä Kiina lienee mennyt jo Kuuban ohi. Kiinan heikkoutena on kuitenkin  tutkimusten yksipuolisuus ja se että vain harva niistä on julkaistu kansainvälisissä julkaisuissa. Jopa noin 70 % Kiinassa tehdyistä tutkimuksista käsittelee selkäkipujen hoitoa, kun Kuubassa ja Saksassa on tutkimuksia tullut varsin tasaisesti useilta lääketieteen osa-alueilta.

 

Tilanne on kuitenkin muuttumassa. Yhä enemmän kiinalaisten tutkimuksia julkaistaan laadukkaissa kansainvälisissä julkaisuissa. Samalla tutkimukset monipuolistuvat eivätkä ne enää keskity pelkkiin selkäoireisiin. Aivan pian Kiina kiilaa niin Saksan kuin Kuubankin ohi ja kenties jättää taakseen myös Venäjän ja Italian. Tästä voi olla myös pientä haittaa otsoniterapian leviämiselle, sillä se saattaa samalla leimautua jonkinlaiseksi perinteisen kiinalaisen lääketieteen kuriositeetiksi. Perinteistä kiinalaista lääketiedettä kun ei vielä länsimaissa paljoa arvosteta siitäkään huolimatta että monien sikäläisten lääkeyrttien samoin kuin vaikkapa akupunktionkin teho on jo melko yleisesti tunnustettu länsimaissakin ainakin tiettyjen oireiden hoidossa. Ja otsoniterapiahan ei missään tapauksessa ole mitään kiinalaista lääketiedettä. Se on lähtöisin Euroopasta. Vanhimmat tutkimukset tulevat jo 1850-luvulta Englannista ja vuosikymmeniä merkittävin otsoniterapiamaa oli Saksa, kunnes Italia ja Venäjä menivät ohi. Kiinalaiset ainoastaan tutustuivat italialaisten menetelmiin ja aloittivat tutkimukset kotimaassaan. Uudet tutkimukset ovat toki aina tervetulleita - sama se mistä ne tulevat.

 

Loppuun siis liitän luettelon Kiinassa tehtyihin tutkimuksiin, joista itse löysin tutkimusviitteen tai jopa kokotekstin jostain tietokannasta. Oheinen lista lienee kuitenkin vain suuntaa antava. Todennäköisesti julkaisuja on huomattavasti enemmän, mutta kiinaa taitamattomana minun on hankala etsiä materiaalia. Esimerkiksi CNKI-tietokannassa oli arviolta 10-20 kongressijulkaisua otsoniterapioista. Julkaisujen nimet, abstraktit ja muu oleellinen tieto oli kuitenkin poikkeuksetta kirjoitettu kiinaksi, joten jätin ne suosiolla lisäämättä, vaikka kääntäjän avulla se olisi saattanut onnistuakin. Useista artikkeleista edes otsikkoa ei ole kirjoitettu englanniksi - saati sitten abstraktia tai kokotekstiä. Luonnollisesti sellaisia artikkeleita en löydä edes vahingossa. Sitten on lukuisia tutkimuksia, jotka koskevat eri taudinaiheuttajien desinfiointia otsonilla. Desinfioivilla ominaisuuksilla on toki lääkinnällisiä sovellutuksia, mutta myös teollisia ja hygieniaan liittyviä, joten jätin nekin artikkelit lisäämättä listaan. Siitä huolimatta tuokin osoittaa, että otsonitutkimus Kiinassa on jo kovassa vauhdissa.

 

Lista on tehty Zotero-tutkimusohjelman avulla sinne lisättyjen tietojen pohjalta. CNKI-tietokanta ei kerro artikkelien sivunumeroita, ja mikäli en ole niitä muualtakaan löytänyt, en niitä ole voinut lisätä Zoteroonkaan. Näin ollen puuttuvien sivunumeroiden vuoksi Zotero lisää viitteen loppuun automaattisesti linkin, josta voi hakea mahdollista lisätietoa. Tämän vuoksi joidenkin viitteiden perässä on linkki juuri CNKI:n sivuille.

 

Lista Kiinassa suoritetuista otsoniterapiatutkimuksista vuoteen 2010 mennessä

 

An, Liangmin, and Liandi Li. “[A clinical observation of combining Ozone and Adefovir to treatment for hepatitis B].” China Modern Medicine 2, no. 14 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGUD200914010.htm. 

An, Liangmin, Yabing Guo, Jie Peng, Fanyi Meng, and Fuyuan Zhou. “[Application of medical ozone in acute exacerbations of hepatitis B of 1 case of lymphoma chemotherapy].” China Modern Medicine, no. 13 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGUD200913056.htm.

Bo, Wu, Chen Longyi, Tang Jian, Huang Guangfu, Feng Hailong, Liu Weidong, and Tan Haibin. “A pyogenic discitis at c3-c4 with associated ventral epidural abscess involving c1-c4 after intradiscal oxygen-ozone chemonucleolysis: a case report.” Spine 34, no. 8 (April 15, 2009): E298-304. 

Cao, Renhui. “[C-arm-guided minimally invasive treatment of discogenic low back pain ozone].” China Modern Medicine, no. 22 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGUD201022018.htm. 

Chen, Feng-jia. “[Observing the Effect of Ozone on 132 Cases Bacterial Vaginal Diseases].” Hebei Medicine 11, no. 11 (2005). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HCYX200511025.htm.

Chen, Lin-rong, and Mei-lian Chen. “[Comparative observation on the effect of ozone solution and conventional drugs on cervicitis].” China Tropical Medicine, no. 8 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-RDYX200608051.htm. 

Chen, Ze, De-qing Zeng, and Zhong-xian Wan. “[Clinical investigation of ozone therapy in protrusion of lumber or cervical intervertebral disc].” Practical Journal of Clinical Medicine, no. 4 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-YYLC200604027.htm. 

Chen, Fu-qiang, Dan Hu, Fei Shi, Ping Xie, and Dengbin Al. “[Clinical study of percutaneous injection of intradisc and intervertebral foramen with ozone to treat lumbar disc herniation].” Pain Clinic Journal, no. 2 (2007): 93-96. 

Chen, Xu-qing, Zhu-qing Weng, Hai-tao Tan, Xiang-rong Pan, Kai Zhou, Min-qiang Wei, and Feng-hua Wang. “[Treatment of lumbar disk herniation with in the guidance of small C-arm guiding combined injection of ozone and collagenase].” Guangxi Medical Journal, no. 9 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-GYYX200709004.htm. 

Chen, Fu-qiang, Dan Hu, and Fei Shi. “[Clinical study of percutaneous injection of intradisc and intervertebral foramen with ozone and betamethasone compound to treat lumbar disc herniation].” Journal of Cervicodynia and Lumbodynia, no. 1 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JYTZ200801014.htm. 

Chen, Zhi-yuan, Hui Chen, and Xiu-heng Liu. “[Effects of ozone oxidative preconditioning on HSP70 expression in renal ischemia/reperfusion injury].” Chinese Journal of Experimental Surgery 25, no. 12 (2008): 1543-1545. 

Chen, Hui, Bianzhi Xing, Xiuheng Liu, Bingyan Zhan, Jiangqiao Zhou, Hengcheng Zhu, and Zhiyuan Chen. “Similarities between ozone oxidative preconditioning and ischemic preconditioning in renal ischemia/reperfusion injury.” Archives of Medical Research 39, no. 2 (February 2008): 169-178. 

Chen, Hui, Bianzhi Xing, Xiuheng Liu, Bingyan Zhan, Jiangqiao Zhou, Hengcheng Zhu, and Zhiyuan Chen. “Ozone oxidative preconditioning inhibits inflammation and apoptosis in a rat model of renal ischemia/reperfusion injury.” European Journal of Pharmacology 581, no. 3 (March 10, 2008): 306-314. 

Chen, Hui, Bianzhi Xing, Xiuheng Liu, Bingyan Zhan, Jiangqiao Zhou, Hengcheng Zhu, and Zhiyuan Chen. “Ozone oxidative preconditioning protects the rat kidney from reperfusion injury: the role of nitric oxide.” The Journal of Surgical Research 149, no. 2 (October 2008): 287-295. 

Chen, Wen-jun, Xiao-mei Zhao, and Hui-ping Zuo. “[Percutaneous Plasma Sword and Ozone Combine to Cure Prolapse of Lumbar Intervertebral Disc].” Hebei Medicine, no. 8 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HCYX200908010.ht. 

Chen, Hui, Hua Xu, and Yang-chang Xiong. “[Advances in medical ozone].” International Journal of Anesthesiology and Resuscitation 30, no. 3 (2009): 258-261. 

Cui, Feng-de, and Liang Feng. “[Percutaneous puncture and intra-disc injection of triatomic oxygen for the treatment of lumbar disc herniation].” China Journal of Orthopaedics and Traumatology, no. 3 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGGU200603023.htm. 

Deng, Bing, and Yong Zhu. “[Clinical Comparison of Ozone Injection Alone and Ozone Injection Combined with Collagenase Chemonucleolysis for Lumbar Intervertebral Disc Herniation under CT Guidance].” Chinese Journal of Modern Operative Surgery, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-XDSS201002019.htm. 

Deng, Liuliu, Wumao Wu, and Mei Hong. “[Efficacy of Ozonide in Maternal Perineal Incision Disinfection].” Journal of Nursing Science, no. 1 (2002). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HLXZ200201013.htm. 

Deng, Yu, Zuomei Wu, Yimin Ren, Xinchun Li, Jianxun He, Zhaokun Guan, and Zhiwei Zhong. “[Experimental pathology-MRI study of effects of medical ozone on articular cartilage].” Chinese Journal of Biomedical Engineering 15, no. 5 (2009): 365-370. 

Fang, Jun, Lin Wang, Yu-Wen An, and Pei-Ran Zhou. “[Experimental study on the effect of injured sciatic nerves by local injection medical ozone in rats].” Chinese Journal of Pain Medicine, no. 6 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZTYZ200806017.htm. 

Feng, Chuan-xue, and Guo-cang Hua. “[The observation of efficacy of medical ozone in treatment of glossopharyngeal neuralgia].” Chinese Journal of Primary Medicine and Pharmacy 17, no. 13 (2010): 1736-1737. 

Feng, J Y, X F He, Y Tian, and J L Wang. “Treatment of Patients with Lumbar Disc Herniation by Percutaneous Injection of O2-O3 Mixture under DSA Fluoroscopic Guidance: Clinical Nursing.” International Journal of Ozone Therapy 7, no. 2 (2008): 136-138.

Fu, Zhi-jian, Nai-bao Zhou, and Tao Sun. “[Toxic effects of ozone on rat astrocytes in vitro].” Chinese Journal of Anesthesiology 29, no. 4 (2009): 340-342. 

Gao, Changjun, Lixian Xu, Wei Chai, Xude Sun, Hui Zhang, and Guihe Zhang. “Amelioration of intestinal ischemia-reperfusion injury with intraluminal hyperoxygenated solution: studies on structural and functional changes of enterocyte mitochondria.” Journal of Surgical Research 129, no. 2 (December 2005): 298-305. 

Gao, Changjun, Wei Chai, Lixian Xu, Guihe Zhang, Hui Zhang, Lichun Han, and Xude Sun. “Protective effects of hyperoxygenated solution preconditioning on intestinal ischemia-reperfusion injury in rabbits.” Journal of Surgical Research 135, no. 2 (October 2006): 268-274. 

Gao, Yan-feng, Wei-dong Zhao, Hong-yu Zhang, Yi-fen Ying, and Hong-mei Li. “[A reasonable design and analysis of the therapeutic effect assessment of lumbar disc herniation treated with injection of ozone].” Chinese Journal of Interventional Imaging and Therapy, no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200802011.htm. 

Gao, Changjun, Xude Sun, Guihe Zhang, Hui Zhang, Hui Zhao, Yonghui Yang, Lichun Han, Lixian Xu, and Wei Chai. “Hyperoxygenated solution preconditioning attenuates lung injury induced by intestinal ischemia reperfusion in rabbits.” Journal of Surgical Research 146, no. 1 (May 1, 2008): 24-31. 

Gao, Changjun, Guihe Zhang, Xude Sun, Hui Zhang, Jianke Kuai, Hui Zhao, Linong Yao, et al. “The effects of intravenous hyperoxygenated solution infusion on systemic oxygenation and intrapulmonary shunt during one-lung ventilation in pigs.” The Journal of Surgical Research 159, no. 2 (April 2010): 653-659. 

Geng, Keting, Chipeng Wu, and Meilian Cheng. “[Curative Effect of Ozone Liquid Vaginitis in Treatment].” Chinese Journal of Misdiagnostics, no. 9 (2005). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZWZX200509009.htm. 

Geng, An, Wei Wang, Qiang Ma, Li-Qiong Peng, and Zhong-Hui Liang. “[Ozone therapy combined with sulfasalazine delivered via a colon therapy system for treatment of ulcerative colitis.].” Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University 30, no. 12 (December 20, 2010): 2683-2685. 

Gu, Xi-bing, Xiao-juan Yang, Hong-ying Zhu, Yue-qin Xu, and Xia-ying Liu. “Effect of medical ozone therapy on renal blood flow and renal function of patients with chronic severe hepatitis.” Chinese Medical Journal 123, no. 18 (2010): 2510-2513. 

Guo, Dong-wu, and Xiang-yang Zhang. “[Study on treatment for knee osteoarthritis by medical ozone].” Gansu Medical Journal, no. 1 (2010): 10-11. 

Guo, Wen-bo, Xian-guo Liu, Wei-guo Xu, Wen-quan Zhuang, Yong-hui Huang, and Jian-yong Yang. “[Analgesic effect of ozone on neuropathic pain in rats].” Chinese Journal of Neuromedicine 7, no. 10 (2008): 985-987. 

Han, Jincheng, Yuzuo Qin, Minqiang Fan, Jing Xu, Tao Zhang, and Canhua Zhou. “[Ozone intervention for 32 cases of lumbar intervertebral disc herination under computed tomography monitoring].” Modern Rehabilitation 11, no. 25 (2007): 5006-5007. 

Han, shun-liang, Hui Liu, and Zheng-yin Liao. “[Percutaneous Ozone Intradiscal Injection to Treat Cervical Disc Herniation under CT Guidance].” West China Medical Journal, no. 6 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HXYX200806086.htm. 

He, X. “Decade Review of Ozone Therapy in China.” International Journal of Ozone Therapy 9, no. 2 (2010): 53. 

He, Shirong, and Jinsheng Chen. “[Clinical evaluation of medical ozone injection treating radiohumeral epicondylitis].” Modern Hospital, no. 11 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-XDYU200611025.htm. 

He, Xiao-feng, and Yan-hao Li. “[Ozonetherapy: the past, present and future].” Chinese Journal of Interventional Imaging and Therapy, no. 5 (2005): 389-392. 

He, Xiao-feng, Zhi-jian Yu, Gao-jun Teng, Yan-hao Li, Qing-le Zeng, Yong Chen, Wei Lu, et al. “[Treatment of lumbar disc herniation by using percutaneous intradiscal and paraspinal space injection of O_2-O_3 mixture].” Chinese Journal of Radiology, no. 9 (2003). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGS200309018.htm. 

He, X F, Z J Yu, Y H Li, W Lu, Q L Zeng, Y Cheng, W D Kong, X L Xu, L Li, and J Pen. “Percutaneous Injection of Intradiscal and Paraspinal Space with O2-O3 Mixture to Treat Lumbar Disc Herniation.” Rivista Italiana di Ossigeno-Ozonoterapia 2, no. 2 (2003): 135-138. 

He, Xiao-feng, Yan-hao Li, Han-wei Chen, Wei Lu, Yong Chen, Qing-le Zeng, Jian-bo Zhao, Xiao-li Xue, Jing Peng, and Peng Shen. “Intradiscal injection of O_2-O_3 to treat lumbar disc herniations: clinical therapeutic effect analysis with 600 cases.” Chinese Journal of Interventional Imaging and Therapy 2, no. 5 (2005). http://en.cnki.com.cn/Article_en/CJFDTotal-JRYX200505004.htm. 

He, Qing, Feng Du, Tao Li, Hui Luo, Xiao Fang Lei, and Dong Liang. “Report on 602 cases of Percutaneous Ozone Puncture Chemonucleolysis Treating Lumbar Disc Protrusion.” Rivista Italiana di Ossigeno-Ozonoterapia 4, no. 2 (2005): 145-148. 

He, Xue-sen, Yong Li, Yi Fan, Jing-hua Liu, and Jie-qun Fang. “[Ultrasonography changes and the effects observed in ozone treatment of periarthritis humeroscapularis].” Journal of Practical Medical Techniques, no. 11 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYYJ200911009.htm. 

He, Xue-sen, Jie-qun Fang, and Yong Li. “[Ultrasound-guided application of ozone in the value of the treatment of Periarthritis humeroscapularis].” Chinese Journal of Ethnomedicine and Ethnopharmacy 18, no. 13 (2009): 85-88. 

Hua, Guo-chang. “[The Clinical Observation on the Treatment of Avascular Necrosis of Femoral Head with Comprehensive Therapy Dominated by Medical Ozone].” International Journal of Triditional Chinese Medicine 31, no. 2 (2009): 146-147. 

Hua, Shuang-yi, Ren-liang Xu, and Bo Qi. “[Clinical evaluation of lumbar disc heniation treated by percutaneous lumbar discectomy associated with O_3 injection].” Journal of Interventional Radiology, no. 3 (2005). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200503018.htm. 

Hu, Guangjian, and Xiguang Feng. “[Clinical Observation of ozone treatment for lumbar disc herniation].” Proceeding of Clinical Medicine, no. 33 (2009): 862-864. 

Huang, Peng. “[Clinical observation of ozone treatment for 120 vulvovaginal candidiasis(VVC) cases].” Acta Medicinae Sinica, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-GLYX201002021.htm. 

Huang, Ping, Dan Wang, Xin-hao Jiang, Qin-shi Yuan, and Yi Liu. “[Therapy of lumbar disc herniation with pereutaneous ozone injection].” Orthopedic Journal of China, no. 11 (2008): 861-863. 

Huang, Xin-quan, Cong-ping Wang, and Ji-tao Yi. “[Clinical Value of Treating Cervical Vertebrae Disc Herniation with Plasma Radiofrenquency Ablation Combined with Ozone].” Journal of Hubei Institute for Nationalities (Medical Edition), no. 1 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-FBMZ201001014.htm. 

Huang, Hua-jun, Bin Yu, Qing-rong Lin, Bo-wei Wang, and Hui-qiang Chen. “[Effect of ozone water on the inflammation and repair in infected wounds].” Journal of Southern Medical University 30, no. 3 (2010): 515-518. 

Hu, Xing-rong, Ji-quan Zhang, and Jun Zhang. “[Treatment of Lumbar Disc Herniation with CT Guided Ozone Injection and Radiofrequency Thermocoagulation].” Radiologic Practice, no. 8 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-FSXS200808034.htm. 

Hu, Qing, Zhi-jun Xia, Ying Zhao, and Xu Chen. “[Application of ozone water in vagina preparation before gynecological transvaginal operation].” Practical Pharmacy and Clinical Remedies 12, no. 6 (2009): 410-411. 

Hu, Wei-hua, An-min Chen, Feng-jing Guo, and Feng Li. “[Efficacy of ozone combined with collagenase for lumbar intervertebral disc protrusion].” Journal of Practical Medicine, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYYZ201002025.htm. 

Huo, D, Y Yang, F Ao, W Dai, L Li, and Y Guo. “[Protective effect of medical ozone and Chinese medicine on acetaminophen-induced toxic hepatitis in dogs].” Shijie Huaren Xiaohua Zazhi 15, no. 3 (2007): 282-286. 

Jiang, Li, and Bao-sen Zheng. “[Effect of ozone on rabbit intervertebral disc cell in different concentration at different timepoints].” China Medicine 4, no. 10 (2009): 792-793.

Jiang, Tao, Shi-wu Yin, Xing-gang Ding, Yu-ping Bi, You-jin Feng, and Yan-liang Li. “[Clinical application of percutaneous oxygen-ozone injection for senile lumbar intervertebral degeneration].” Contemporary Medicine (Chinese Journal of Interveation Radiology), no. 3 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRUF200803029.htm. 

Jiang, Jian-wei, Qing-hua Wu, Zhen-hai Wu, Xin-sheng Li, Gang Cheng, and Chen Gu. “[Percutaneous intradiscal oxygen-ozone(O3)multipoint injection: an experimental study in conies].” Acta Universitatis Medicinalis Nanjing (Natural Science), no. 4 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-NJYK200904043.htm. 

Jiao, Xiu-juan, and Xun Pehn. “[Theoretical Basis and Clinic of Medical Ozone in Therapy].” Chinese Journal of Misdiagnostics 10, no. 7 (2010): 1537-1538. 

Jiao, Xiu-juan, and Xun Peng. “[Clinical study of medical ozone therapy in chronic hepatitis B of 20 patients].” Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi = Zhonghua Shiyan He Linchuang Bingduxue Zazhi = Chinese Journal of Experimental and Clinical Virology 22, no. 6 (December 2008): 484-485. 

Kang, Jilong, Aiyue Pei, Ming Fang, Guishu Lin, and Wenzhe Jin. “[Efficacy of medical ozone tender spot injection combined with passive functional exercise on scapulohumeral periarthritis].” Clinical Medicine, no. 8 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-EBED200908015.htm. 

Li, Rui-qin. “[Spiral CT guided O3 injection for the treatment of lumbar disc herniation].” Journal of Shandong Medical College, no. 3 (2009): 204-208. 

Liang, Cheng-yi. “[Clinical Effect of Ozone in Treating Knee Osteoarthritis].” Heilong Jiang Medical Journal, no. 7 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HLYX200907025.htm. 

Liang, Chan-bo, and Jian-ning Huang. “[Comprehensive ozone treatment and nursing of patients with infected diabetic foot ulcer].” International Journal of Nursing 29, no. 7 (2010): 980-982. 

Li, Jiliang, Jianchun Zhao, and Xin Wang. “[Treatment of lumbar disk herniation with CT guiding injection of oxygen-ozone].” Journal of Practical Medical Imaging, no. 6 (2004). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYXY200406013.htm. 

Li, Xiao-hong, Wei-cheng Zhao, and S mok Martin. “[Spinal ozone injection in the treatment of low back pain].” Pain Clinic Journal, no. 4 (2005). http://en.cnki.com.cn/Article_en/CJFDTOTAL-TTXZ200504014.htm. 

Li, Shao-hui, Ge Yu, and Gui-qin Chen. “[Impact of different concertrations of ozone injection on pathological changes of rabbit skeletal muscle].” Journal of Modern Clinical Medical Bioengineering, no. 6 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-XDLC200606012.htm. 

Li, Jiliang, Xin Wang, Jianchun Zhao, and Shouchun Cui. “[Combined injections of ozone(O_3) and collagenase in the treatment of herniated lumbar disk].” Journal of Practical Medical Imaging, no. 3 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYXY200603023.htm. 

Li, Li, Qiao-hua Zhang, and Shu-ling Hou. “[Effect of ozone therapy on T-lymphocyte subsets,NK cell in the patients with lymphoma].” Journal of Shanxi Medical University, no. 3 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SXYX200703007.htm. 

Li, Cheng-li, Le-bin Wu, Ji-qing Song, Yu-bo Lu, Yu-jun Xu, and Chuan-chen Zhang. “[Treatment of lumbar disk herniation with MRI guidance injection of oxygen-ozone].” Chinese Journal of Radiology, no. 6 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGS200706034.htm. 

Li, Li-Jie, Yun-Gao Yang, Cheng Wang, Zhi-ling Zhang, Di Huo, He-yu Hua, Pei-chan Chen, Hong-shuan Zhang, and Ya-bing Guo. “[Protective effect of Yigan Fuzheng Paidu capsules combined with ozone on CCl4-induced acute hepatic injury in dogs].” Journal of Southern Medical University, no. 5 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-DYJD200705035.htm. 

Li, Hanjin, Keshou Geng, Chipeng Wu, Meilian Chen, Lin Fang, Miaoru Chen, Caiqiong Zhang, et al. “[Curative Effect of Ozone Liquid Vaginitis in Treatment].” International Medicine & Health Guidance News 13, no. 3 (2007): 4-7. 

Li, Li-Jie, Yun-Gao Yang, Zhi-Ling Zhang, Sui-Feng Nie, Ze Li, Feng Li, He-Yu Hua, Yan-Jun Hu, Hong-Shuan Zhang, and Ya-Bing Guo. “Protective effects of medical ozone combined with traditional Chinese medicine against chemically-induced hepatic injury in dogs.” World Journal of Gastroenterology: WJG 13, no. 45 (December 7, 2007): 5989-5994. 

Li, Jia-kai, Yue-yong Xiao, Jin-shan Zhang, Jin-lin Tian, and Bo Yang. “[CT-guided Ozone Injection for the Treatment of Lumbar Disc Herniation:the Impact of the Ozone Distribution Patterns on the Efficacy].” Chinese Journal of Medical Imaging, no. 6 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZYYZ200806013.htm. 

Li, Zai-bao, Zhen-xiao Sun, and Mei-xia Liu. “[Percutaneous laser disc decompression and ozone dissolution in treating herniation of cervical disc].” Journal of Shandong Medical College, no. 6 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCYB200806019.htm. 

Li, Cheng, Jing Yu, Ming Liu, Le-bin Wu, Yu-bo Lu, Jie Huang, Ji-qing Song, Shou-gang Bao, Zhen Qi, and Qian-qian Cao. “[MR imaging-guided minimally invasive surgery for treament of posterolateral lumbar disc herniation via facet joint medial route].” Chinese Journal of Radiology 44, no. 5 (2010). http://eng.med.wanfangdata.com.cn/PaperDetail.aspx?qkid=zhfsx&qcode=zhfsx201005014. 

Liu, Lin, Li-ping Dong, Hua-peng Meng, Xin-xin Li, and Hao Cai. “[PLDD + O_3 Treatment on Cervical Spondylotic Myelopathy].” Chinese Journal of Laser Medicine & Surgery, no. 3 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGJG200703012.htm. 

Liu, Huizuo, Ruihua Han, Zheng Xin, and Yongming Wang. “[Experimental Study on New Type of Ozone Instrument for Cleaning Wound].” Preventive Medicine Tribune 13, no. 10 (2007): 905-906. 

Liu, Wei-bo, Qi-xi Li, and Xiao-feng He. “[Clinical application of medical ozone in interventional therapy of the barrenness of fallopian tube adhesion].” Chinese Journal of Interventional Imaging and Therapy 5, no. 3 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200803013.htm. 

Liu, W-B, Q-X Li, and X-F He. “Clinical Application of Medical Ozone in the Interventional Therapy ​for Infertility Caused by Fallopian Tube Adhesion.” International Journal of Ozone Therapy 8, no. 2 (2009): 198-201. 

Liu, Ming, Cheng-li Li, Yu-bo Lu, Jie Huang, Ji-qing Song, Lei Li, Shou-gang Bao, Qian-qian Cao, and Le-bin Wu. “[MRI-guided percutaneous cervical discectomy and discolysis with oxygen-ozone mixture for treatment of cervical disc herniation: an initial experience].” Chinese Journal of Radiology 44, no. 3 (2010): 312-315. 

Lu, Li-juan, Zhi-qiang Hu, and Ying Han. “[Percutaneous treatment of herniated lumbar disc by intradiscal oxygen-ozone injection under guidence of CT].” Journal of Clinical Anesthesiology, no. 12 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCMZ200712004.htm. 

Lu, Wei, Xiaofeng He, and Quelin Mei. “[Treatment of Huge Lumbar Disc Herniation with Percutaneous Ozone Injection Through Posterolateral and Inner Margin of Facet Joint Approach].” Journal of Clinical Radiology, no. 12 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCFS200812044.htm. 

Lu, Wei, Yan-Hao Li, and Xiao-Feng He. “Treatment of large lumbar disc herniation with percutaneous ozone injection via the posterior-lateral route and inner margin of the facet joint.” World Journal of Radiology 2, no. 3 (2010): 109-112. 

Mao, Ji-Kai, Yu-Bin Liu, and Shu-Feng Wu. “[Radio frequency hot congeal target puncture and Ozone injection for the treatement of lumbar disk herniation].” Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology 21, no. 12 (December 2008): 931-932. 

Meng, Xiao-dong, Guang-zhou Wang, and Yue-yong Xiao. “[Combined injection of collagenase and ozone for treatment of lumbar disk herniation].” Chinese Journal of Interventional Imaging and Therapy, no. 4 (2005). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200504004.htm. 

Nie, Lin, Xue Li, and De-yu Hu. “[Effect of ozone on the remineralization of enamel in vitro].” Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology 42, no. 2 (February 2007): 102-105. 

Niu, Qiaohong, and Shuling Hou. “[Evaluation on curative effect of ozone combined chemotherapy to treat patients with non-Hodgkin lymphoma and nursing care of them].” Chinese Nursing Research 23, no. 10C (2009): 2788-2789. 

Pan, Jin-hua, Hong-yu Liu, and Nong He. “[Application of Ozone in the treatment of herpes zoster].” China Clinical Practical Medicine 3, no. 4 (2009): 116-117. 

Peng, Zhi-kang, Wen-zhi Luo, Wei-fang Lu, Zhi-jian Yu, Ya-hong Liu, and Zheng-bing Zhu. “[Percutaneous lumbar disectomy integrated with medical ozone for treatment of lumbar disc herniation].” Chinese Journal of Neuromedicine, no. 12 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-CJON200612019.htm. 

Peng, J, H Xing, B Zhang, F Wu, J Guo, and X-F He. “Analysis of The Efficacy of Ozone Therapy on Lumbar Disc Herniation.” International Journal of Ozone Therapy 8, no. 2 (2009): 206-210. 

Peng, Yong, Meng-Qi Wei, Juan Wu, Jian-shou Zhou, Yong Yang, Hong-liang Zhao, and Ming-guo Shi. “[Ozone therapy for the complex prolapse of lumbar intervertebral disc: a clinical observation].” Journal of Interventional Radiology 19, no. 1 (2010): 62-65. 

Peng, Jing, Hui Xing, Bo Zhang, Feng Wu, Jin-feng Guo, Yan-kun He, Xiaong-li Huang, and Xiaofeng He. “[Ozone injection for the treatment of lumbar disc herniation:a therapeutic analysis of 104 cases].” Journal of Interventional Radiology, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS201002009.htm. 

Peng, Zhi-kang, Ya-hong Liu, Wei-fang Lu, and Zhi-jian Yu. “[Percutaneous lumbar discectomy combined with medical ozone in the treatment of lumbar disc herniation].” Chinese Journal of Neuromedicine 9, no. 9 (2010): 955-958. 

Qu, Qun-wei, Xiu-jian Liu, shao-ming Zhu, Shen-ping Yuan, and Xiao-ying Xue. “[Impact of different injection methods on ozone distribution in intervertebral discs and curative effect].” Chinese Journal of Interventional Imaging and Therapy, no. 4 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX201004027.htm. 

Ren, Yi-min, Jian-biao Shang, Xiao-mei Wu, yong-fu Chen, and Xiao-feng He. “[Treatment of periarthritis humeroscapularis with medical ozone injection].” Chinese Journal of Interventional Imaging and Therapy, no. 5 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200605005.htm. 

Ren, Feng-qi, Bu-jin Shi, Jin-ping Zhao, and Yi-qing Wang. “[Study on the ozone dose used for the injection therapy of lumbar intervertebral disc protrusion].” Journal of Interventional Radiology, no. 3 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS201003025.htm. 

Shao, Ming-li. “[Clinical study of percutaneous treating lumbar disc herniation by CT-guided with O_3 injection].” Chinese Imaging Journal of Integrated Traditional and Western Medicine, no. 2 (2008). http://en.cnki.com.cn/Journal_en/E-E058-JHYX-2008-02.htm. 

Shen, Hui-min, Yue-bo Yang, and Xiao-xia Liu. “[Observation on the effect of ozone on vulvovaginal candidiasis and bacterial vaginosis].” China Tropical Medicine, no. 5 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-RDYX200705038.htm. 

Shen, Huimin, yuebo Yang, and Min Huang. “[Evaluation on the therapeutic effects of ozone for the treatment of bacterial vaginosis].” Medical Journal of Chinese People's Liberation Army, no. 5 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JFJY200705038.htm. 

Shen, Wen-long, Li Du, and Shu-tian Liu. “[Percutaneous Ozone Chemonucleolysis for Treating Lumbar Disc Herniation].” Applied Journal of General Practice, no. 9 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYQY200809023.htm. 

Shi, Bujin, and Jinping Zhao. “[Clinical Study of Injection of Ozone in Lubar Intervertebral Disc Herniation].” Modern Medical Imagelogy, no. 4 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-XDYY201004016.htm. 

Shi, Yonghao, Yongwei Wen, and Wei Wang. “[Clinical analysis of ozone therapy for mammary abscess].” Modern Hospital 9, no. 10 (2009): 37-38. 

Sun, Xi-xia, Qian Zha, and Rong-chao Li. “[Short-term effects of ozone ablation under guidance of CT on the lumbar intervertebral disc protrusion].” Pain Clinic Journal, no. 1 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-TTXZ200701008.htm. 

Sun, Gang, Xun-wei Liu, Peng Jin, Run-song Hao, Fan-dong Li, Zhi-yong Xie, Yu-hai Yi, and Xu-ping Zhang. “[Primary application of CT guided O_2-O_3 mixture for treatment of lumbar disc prolapse with].” Contemporary Medicine (Chinese Journal of Interveation Radiology), no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRUF200802021.htm. 

Sun, Jian-ping, Hong-yu Liu, and Nong He. “[Epidural Application of Ozone in the Treatment of Herpes Zoster Neuralgia].” China Clinical Practical Medicine 4, no. 1 (2010): 28-29. 

Sun, Yunqiang, Fugen Wang, Yan Sun, Shenyi Liu, and Hongzhi Zhang. “[Lumbar Disc Herniation Treated with Percutaneous Laser Disc Decompression and Ozone Injection by Bilateral Operative Approach].” Chinese Journal of Laser Medicine & Surgery 19, no. 1 (2010): 32-34. 

Tan, Chuan-yun. “[Effects of Ozone Therapy on Vulvovaginal Candidiasis].” Journal of Tropical Medicine 9, no. 12 (2009): 1422-1423. 

Tan, Hua-bing, and Xi Wu. “[Progress in Experiments and Clinical Research of Ozone by Percutaneous Puncture in Dorsal Disc Prolapse].” Chinese General Practice, no. 6 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-QKYX200906036.htm. 

Tan, Qing-qiang, Ming-dao Li, Guo-lan Wu, Xiong Zhu, and Ping-ping Wang. “[Treatment of interbody space infection after discectomy with ozone].” Journal of Clinical Orthopaedics 12, no. 2 (2009): 233. 

Tian, Jin-lin, jin-shan Zhang, Yue-yong Xiao, Jiang-tao Liu, Bo Yang, Jia-kai Li, and Miao Yu. “[Oxidative effect of different concentration of ozone injected into porcine normal lumbar disks].” Chinese Journal of Interventional Imaging and Therapy, no. 4 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200704018.htm. 

Tian, Jin-lin, Jin-shan Zhang, Yue-yong Xiao, Jiang-tao Liu, Bo Yang, Jia-kai Li, and Miao Yu. “[Effect of high concentration ozone to cerebrospinal fluid and spinal cord after injection into subarachnoid space: an experimental study in pigs].” Chinese Journal of Interventional Imaging and Therapy, no. 4 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200704019.htm. 

Tian, J L, J S Zhang, Y Y Xiao, J T Liu, B Yang, J K Li, and M Yu. “Changes of CSF and spinal pathomorphology after high-concentration ozone injection into the subarachnoid space: an experimental study in pigs.” AJNR. American Journal of Neuroradiology 28, no. 6 (July 2007): 1051-1054. 

Tian, Jin-lin, Jin-shan Zhang, Yue-yong Xiao, Jiang-tao Liu, Bo Yang, Jia-kai Li, and Miao Yu. “[Comparison of effect between ozone injection and laser decompression in disks of pigs].” Chinese Journal of Interventional Imaging and Therapy, no. 5 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200805006.htm. 

Wang, Yan, and Gang Liu. “[Ozone ablation treatment in diskal hernia under CT guidance(reports of 223 cases)].” Journal of China Clinic Medical Imaging, no. 3 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LYYX200803026.htm. 

Wang, Yun-tao, and Bao-sen Zheng. “[Comparative observations on X-ray-guided injection of ozone treatment for two kinds of disc derived low back pain].” Acta Academiae Medicinae CPAPF, no. 12 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-WUXB200812007.htm. 

Wang, Zhu Ying, Cai Mei Jiang, and Zhi Min Wang. “Percutaneous Treatment of Lumbar Disc Herniation by Oxygen-Ozone Injection: A Clinical Study of 322 Cases.” Rivista Italiana di Ossigeno-Ozonoterapia 4, no. 1 (2005): 6-8. 

Wang, Zhu-ying, Cai-mei Jiang, and Zhi-min Wang. “[Percutaneous treatment of lumbar disc herniation by oxygen-ozone injection-clinical study with indication].” Journal of Interventional Radiology, no. 2 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200602005.htm. 

Wang, Chang-sui, Shu-tang Wang, and Jing-xue Wang. “[Clinical Application of Ozone in Treating the Recurrent Herniated Lumbar Disc after Surgery].” Journal of Practical Radiology, no. 12 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYFS200712034.htm. 

Wang, Da-jian, Lei Zhang, and Xin-min Wang. “[Treatment of huge lumbar intervertebral disc herniation with ozone and collagenase through the route of inner margin of facet joint].” Pain Clinic Journal, no. 1 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-TTXZ200701007.htm. 

Wang, Junhua, Haifeng Li, and Gang Wang. “[Studies on the concentration of oxygen-ozone in percutaneous intradiscal oxygen-ozone-injection for the treatment of lumber disc herniation].” Chinese Journal of Spine and Spinal Cord, no. 11 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZJZS200711010.htm. 

Wang, Da-jian, Lei Zhang, and Chun-ting Wang. “[Treatment of lumbar intervertebral disc herniation by ozone combined with collagenase injected into disc].” Pain Clinic Journal, no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-TTXZ200802006.htm. 

Wang, Bing-liang, Wei Sun, and Hua-bing Zhu. “[Treatment of lumbar disc protrution by percutaneous diskectomy with injection of medical ozone: the short-term clinical result].” Contemporary Medicine (Chinese Journal of Interveation Radiology), no. 1 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRUF200801023.htm. 

Wang, Ming-ming, Si-xue Zhou, and Hui Li. “[Percutaneous Laser Disk Decompression Combining Ozone Nucleus Gelatinosus Oxidizing Technique Treats Lubar Intervertebral Disc Protrusion].” Journal of Xiangnan University (Medical Sciences), no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-CZYG200802005.htm. 

Wang, Wei, He-ji Cao, and Li-peng Ji. “[Clinical applications of radiofrequency thermocoagulation combined with ozone nucleus pulposus ablation in treatment of lumbar disc herniation].” Journal of Huaihai Medicine, no. 5 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HHYY200805000.htm. 

Wang, Xing-hua, Hong-wei Bao, and Xin-guo Chen. “[Evaluation of the treatment of lumbar disc herniation treated with percutaneous lumbar disectomy and 03 injection].” Pain Clinic Journal, no. 4 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-TTXZ200804004.htm. 

Wang, Ying, Yue-yong Xiao, Jin-lin Tian, Jia-kai Li, and Xiao-dong Meng. “[Physical therapy in prevention of postoperative symptom setback of ozone ablation of lumbar herniation].” Chinese Journal of Interventional Imaging and Therapy, no. 5 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200805005.htm. 

Wang, Xuesong, Yanjiang Dong, and Chao Song. “[Percutaneous Cervical Disc Ozone Chemonucleolysis In the Treatment of Cervical Disc Herniation 11 Cases of Analysis].” China Foreign Medical Treatment, no. 18 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HZZZ200918008.htm. 

Wang, Xuan, Liangjun Zhong, and Shuangyun Zhao. “[An evaluation of the monitor effect of a laser-fluorescent device during executing the ozone-remineralization treatment to dental caries of deciduous tooth].” Journal of Practical Stomatology 25, no. 6 (2009): 898-900. 

Wang, Hong, Jun Tong, Ruixia Li, Lingling Xing, and Xiuli Liang. “[Ozone Therapy for Vaginal Infection and Nursing Care].” Journal of Nursing Science 24, no. 8 (2009): 56-57. 

Wang, H-T, H-G Zhou, H-B Zhang, P-Z Jiang, S-M Jia, J-T Zhao, R Liu, Y-H Zhang, and X-F He. “Clinical Value of Dsa-Guided Combined Injection of Ozone and Collagenase in Treating Lumbar Disc Herniation.” International Journal of Ozone Therapy 8, no. 2 (2009): 202-205. 

Wang, Ai-xiang, Shu-min Long, Wan-peng Fang, Zhong Chen, and Jian-zhong Chen. “[Combination of Ozone and Collagenase as a Treatment of Prolapse of Lumbar Intervertebral Disc].” Journal of Anhui Health Vocational & Technical College, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-AHWZ201002021.htm. 

Wang, Luanling, Zhaoyan Xie, and Fengyou Huang. “[Curing effect of high concentration ozone solution on female recurrent vulvovaginal candidosis].” CNKI:SUN:RDYZ.0.2009-12-025, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-XDYU201002019.htm. 

Wang, Zhi-xin, Xiao-wei Yang, and Xin Luo. “[Clinical observation of ozone therapy for the vulvovaginal candidiasis].” Journal of Jinan University (Natural Science & Medicine Edition), no. 2 (2010): 200-202. 

Wang, Jian-wei, Ya-feng Zhang, Yong Ma, Bing Xu, Qing Wang, and Heng Yin. “[Therapeutic Effect of Low Concentration Medical Ozone on Knee Osteoarthritis].” Journal of Liaoning College of Traditional Chinese Medicine 12, no. 4 (2010): 17-19. 

Wang, Ling, Chunran Liu, Hui Zhang, Changjun Gao, Wei Chai, Ruifen Xu, Hui-xia Wang, and Lixian Xu. “Intravenous administration of hyperoxygenated solution attenuates pulmonary edema formation in phosgene-induced acute lung injury in rabbits.” The Journal of Surgical Research 164, no. 1 (November 2010): 131-138. 

Wei, Chuan-jun, Yan-hao Li, Yong Chen, Jiang-yun Wang, Qing-le Zeng, Jian-bo Zhao, and Que-lin Mei. “[Percutaneous intradiscal oxygen-ozone injection for lumbar disc herniation: no need of perioperative antibiotic prophylaxis].” Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University 27, no. 3 (March 2007): 384-386. 

Wei, Xing, Zheng-yin Liao, and Yi-sen Yang. “[Cervical disc herniation percutaneous radiofrequency thermal ablation with medical ozone ablation clinical analysis of 31 cases].” Sichuan Medical Journal, no. 10 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SCYX200910040.htm. 

Wei, Meng-Qi, Jian-Shou Zhou, Hai-Tao Liu, Yuan Yuan, Jun-Qing Xu, Yong Yang, Jin-Song Zhang, Yong Peng, and Yi Huan. “Clinical investigation of CT-guided ozone-blowing and fumigation therapy for the chronic refractory cutaneous sinus and ulcer.” African Journal of Biotechnology 9, no. 22 (2010): 3334-3337. 

Wu, Jin-ping, Zheng-kan Chen, Xu-dong Jiao, Hui Wu, and Lu-xi Zhang. “[Percutaneous treatment of lumbar disc herniation by injection of medical ozone].” Acta Academiae Medicinae Wannan, no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-WNYX200802027.htm. 

Wu, Qing-hua, Jian-wei Jiang, Zhen-hai Wu, Xin-sheng Li, and Gang Cheng. “[Oxygen-ozone injection for the treatment of lumbar disc herniation:clinical therapeutic effect analysis with 162 cases].” Acta Universitatis Medicinalis Nanjing (Natural Science), no. 4 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-NJYK200804038.htm. 

Wu, Chunyin, Jiahua Chen, and Song Wang. “[Curative effect of combined injections of ozone and collagenase in the treatment of lumbar disc herniation].” Acta Universitatis Medicinalis Anhui, no. 4 (2008): 452-455. 

Wu, Zhiqun, Long Xiao Wei, Jun Li, Yiqing Wang, Daihui Ni, Peng Yang, and Yuhai Zhang. “Percutaneous treatment of non-contained lumbar disc herniation by injection of oxygen-ozone combined with collagenase.” European Journal of Radiology 72, no. 3 (December 2009): 499-504. 

Wu, Hangqing, Shihui Zhu, and Bing Ma. “[Effect of ozone solution on healing and anti-infection of deep partial thickness burn wound].” Jiangsu Medical Journal, no. 2 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-YIYA201002010.htm. 

Xiao, Cai wen, Jing xue Ma, Shen Xu, Yu xiang Fan, Si qing Hou, Yun dong Yang, Hui lai Cui, and Jun Chen. “[The experimental study of keratomycosis treated by Ozone solution].” Chinese Journal of Practical Ophthalmology, no. 12 (2004). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZZZY200412041.htm. 

Xiao, Yue-yong, Xiao-dong Meng, Ji-liang Li, and Chun Chen. “[CT guided O_3 injection for the treatment of lumbar disc herniation].” Chinese Journal of Interventional Imaging and Therapy, no. 4 (2005). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200504003.htm. 

Xiao, Yue Yong, Jin Lin Tian, Jia Kai Li, and Jin Shan Zhang. “CT-Guided Ozone Injection for the Treatment of Cervical Disc Herniation.” Rivista Italiana di Ossigeno-Ozonoterapia 5, no. 2 (2006): 109-115. 

Xiao, Cheng-jiang, Jian-nong Han, Xi-yu Wu, Li-heng Li, Pei-ying Wei, and Ya-hui Chen. “[Treatment of lumbar disc protrusion with percutaneous Ozone injection under CT guidance].” Contemporary Medicine, no. 17 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-DDYI201017032.htm. 

Xie, W, L Zhang, and R Yang. “[The role of ozone solution on debridement and sterilization of burn wound].” Zhonghua Shao Shang Za Zhi = Zhonghua Shaoshang Zazhi = Chinese Journal of Burns 16, no. 3 (June 2000): 163-165. 

Xi, Xiu-e, Hao-zhen Shang, and Jin-sheng Wang. “[The clinical study on the curative effect of 20 refractory tuberculosis treated by ozone and chemotherapy].” Medical Information: Section of Operative Surgery, no. 5 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-YXSS200905012.htm. 

Xu, Lin, Shoujun Yang, and Xiaoli Li. “[Clinical Application of Radio Frequency Ablation Combined Ozone Injection in Treating Cervical Disc Herniation].” Journal of Clinical Radiology, no. 11 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCFS200711026.htm. 

Xu, Wei-guo, Wen-quan Zhuang, Jian-yong Yang, and Wei Chen. “[Clinical Analysis of Treatment of Lumbar Disc Herniation with Medical Ozone and Chemonucleolysis].” Journal of Practical Radiology, no. 6 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYFS200706028.htm. 

Xu, Wei-guo, Jian-yong Yang, Wen-quan Zhuang, Wei Chen, and Jia-ping Li. “[Clinical comparison of treatment of lumbar disc herniation with medical ozone and PLD].” Journal of China Clinic Medical Imaging, no. 4 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LYYX200704025.htm. 

Xu, R F, T T Li, X Y Feng, H Zhang, B Song, C R Liu, and L X Xu. “Therapeutic effect of hyperoxygenated solution on acute lung injury induced by oleic acid.” European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes 41, no. 1 (2008): 37-43. 

Xu, L, Z-L Li, X-F He, D-C Xiang, J Ma, C-J Hong, J-X He, L Yang, Z-H Gong, and J Qiu. “Evaluation of the Clinical Curative Effect of an O(2)-O(3) mixture to Treat Lumbar Disc Herniation with Different Treatment Sessions.” Interventional Neuroradiology: Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences 15, no. 2 (July 29, 2009): 159-163. 

Yang, Xiao-lin, Xiu-hua Miao, and Zhen-hua Ruan. “[Treatment of Lumbar Disc Herniation with CT Guiding Injection of Oxygen-ozone and Collagenase].” Hebei Medicine, no. 11 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HCYX200611011.htm. 

Yang, Shuling, Bing Li, and Junhua Yun. “[A case of chronic hepatitis B treated with ozone].” Chinese Nursing Research, no. 8 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SXHZ200608076.htm. 

Yang, An-li, Liang Liu, Meng-wei Yao, Min-wei Cai, and Feng Cai. “[Clinical value of treating lumbar disc herniation with plasma radiofrenquency ablation combined with ozone].” Journal of Clinical Medicine in Practice, no. 1 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-XYZL200701000.htm. 

Yang, Yan, Yuzuo Fan, Juan Wu, Zuoying Lu, and Yi Liu. “[Clinical study of interferon α-2b combined with ozone therapy in the treatment of chronic hepatitis B].” Qianwei Journal of Medicine & Pharmacy, no. 1 (2007): 3-6. 

Yang, Shi-zhong, Deng-ai Li, and Cun-liang Niu. “[The discussion on problems of ozone ablation in treatment of lumbar intervertebral disc herniation].” Chinese Journal of Postgraduates of Medicine, no. 11 (2008): 33-35. 

Yang, An-li, Hua-ming Xue, Feng Cai, and Liang Liu. “[Minimally invasive nucleoplasty combined with Oxygen-Ozone therapy for the treatment of lumbar disc herniation].” Orthopedic Journal of China 16, no. 23 (2008): 1818-1821. 

Yang, Shuling, Junhua Yin, and Hongyan Xie. “[Curative effect evaluation and nursing care of patients with chronic hepatitis B treated with medical ozone].” Chinese Nursing Research, no. 4 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SXHZ200904023.htm. 

Yang, Yuan-liang, Guang-yuan Chen, and Jie-zhu Liang. “[Study of Percutaneous Injection of Ozone into Articular Cavity in the Treatment of Animals with Osteo-arthritis].” China Clinical Practical Medicine 3, no. 7 (2009): 12-13. 

Yin, Chang-Bao, and Bi-Fa Fan. “[Effects of ozone with different concentrations on intervertebral disc in rabbits].” Chinese Journal of Pain Medicine, no. 4 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZTYZ200704011.htm. 

Yin, Shi-wu, Ting-miao Xiang, and Lu-an Ye. “[Percutaneous treatment of lumbar disc herniation by injection of medical ozone].” Journal of Interventional Radiology 15, no. 6 (2006): 555-556. 

Yin, Shiwu, Tingmiao Xiang, and Huilin Zhang. “[The value of discography in the interventional treatment of lumbar disc herniation by medical ozone].” Anhui Medical Journal, no. 3 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-AHYX201003031.htm. 

Yu, Zhijian, Xiaofeng He, and Yong Chen. “[Influence of ozone on the ultrastructures of nucleus pulposus].” Journal of Interventional Radiology, no. 3 (2001). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200103017.htm. 

Yu, Zhijian, Xiaofeng He, Yong Chen, Qingle Zeng, Chihong Liu, Zhongqing Zhao, Yong Lu, and Yanhao Li. “[Percutaneous intradiscal ozone (O_3)-injection:an experimental study in canines].” Chinese Journal of Radiology 50, no. 4 (2002). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGS200204023.htm. 

Yu, Zhijian, Xiaofeng He, and Shicheng He. “[Treatment of Lumbar Disc Herniation with O_3 Injection: Correlation of O_3 Distribution Pattern in Disc with Therapeutic Effect].” Journal of Clinical Radiology, no. 10 (2003). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCFS200310025.htm. 

Yu, Zhijian, Xiaofeng He, and Bo Yang. “[Treatment of Lumbar Disc Herniation with Medical Ozone: Management of Postoperative Symptom Setback].” Journal of Clinical Radiology, no. 10 (2004). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LCFS200410021.htm. 

Yu, Zhi-jian, Xiao-feng He, and Yang-hao Li. “[Treatment of lumbar disc herniation with medical ozone].” Chinese Journal of Medical Imaging Technology, no. 4 (2004). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZYXX200404048.htm. 

Yu, Zhijian, Wenzhi Luo, Xiaofeng He, Zhikang Peng, and Yanhao Li. “[Long-term effect of medical ozone in the treatment of lumbar disc herniation].” Chinese Journal of Neuromedicine 8, no. 10 (2009): 1046-1049. 

Yu, B, Q-R Lin, B-W Wang, Q Zhu, and X-F He. “Effect of Intra-Articular Ozone Injection on Degenerative Knee Cartilage in Rats.” International Journal of Ozone Therapy 9, no. 1 (2010): 14-20. 

Yu, B, Q-R Lin, B-W Wang, Y-F Zhang, and X-F He. “Bacterial Culture Experiments of Medical Ozone.” International Journal of Ozone Therapy 9, no. 2 (2010): 59-62. 

Zeng, Zhiqiang, Jianping Zeng, Zhenhua Xie, Jirun Zheng, and Songping Huang. “[CT-guided ozone nucleolysis in the treatment of lumbar disc herniation].” International Medicine & Health Guidance News 16, no. 19 (2010): 2337-2340. 

Zhang, Tian-Ji, and Zheng-yong Yang. “[Ozone combined with collagenase in the treatment of lumbar intervertebral disc herniation].” Journal of Interventional Radiology, no. 12 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200812020.htm. 

Zhang, Wei, Zhi-jian Fu, and Jun-tian Xie. “[Effects of intrathecal ozone on pain threshold, motor function and CSF superoxide dismutase activity and malondialdehyde concentration in rabbits].” Chinese Journal of Anesthesiology, no. 6 (2006). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHMZ200606022.htm. 

Zhang, Wei, Zhi-jian Fu, and Mei-ying Wang. “[Oxygen-ozone and pain clinical].” International Journal of Anesthesiology and Resuscitation, no. 4 (2007): 331-334. 

Zhang, Yan, Feng Chen, and Song Wu. “[Clinical observation on O3 acupoint injection for treatment of low back pain].” Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion 27, no. 2 (February 2007): 115-116. 

Zhang, Ye, Ming-ju Sun, Chui-qi Li, Sai-ming Gao, Chun-hua Lu, Hong-yan Sun, Yan-hui Wang, Gang Li, and Peng Li. “[Effect of percutaneous laser therapy combined with ozone on　lubar intervertebral disc protrusion].” Journal of Navy Medicine, no. 2 (2008). 

Zhang, Hong-yu, Yan-feng Gao, Wei-dong Zhao, Yi-fen Ying, and Hong-mei Li. “[Comparison of therapeutic effect of medical ozone and sodium hyaluronate on rabbit knee osteoarthritis].” Chinese Journal of Interventional Imaging and Therapy, no. 5 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRYX200805007.htm. 

Zhang, Ze-wu, Qiao-li Zhang, and Ke-Ting Geng. “[Study on the treatment of Monilial vaginitis with ozone liquid and its influencing factors].” Maternal and Child Health Care of China, no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZFYB200802005.htm. 

Zhang, Hong-yu, Wei-dong Zhao, and Yan-feng Gao. “[The prevention and disposal method of pain after treatment of LDH with combined injection of collagenase and ozone].” Proceeding of Clinical Medicine 4, no. 11 (2008): 888-890. 

Zhang, Hong-yu, Wei-dong Zhao, and Yan-feng Gao. “[Cartilage's magnetic resonance and electron microscope observation of O_3 treatment of rabbit knee osteoarthritis].” Contemporary Medicine, no. 35 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-DDYI200935048.htm. 

Zhang, Hong-xin, Lan Chen, Heng Wang, Xin-ming Ma, Shi-xin Chen, Jian-ming Peng, Wu-ping Zhang, et al. “[Intradiscal Injection of O3 Combined with Epidural Injection of Collagenase for Treatment of Prominent Lumbar Disc Herniation: A Multicentral Application Observation].” Journal of Practical Radiology 25, no. 3 (2009): 396-400. 

Zhang, Lan-ling, Xiao-qiang Zhuang, Feng-yan Fu, and Fu-sheng Zhou. “[The preliminary clinical study on treatment of liver-stagnation and spleen-deficiency Irritable Bowel Syndrome by medical-ozone].” International Medicine & Health Guidance News, no. 4 (2009): 79-81. 

Zhang, Tao, Bing-chuan Yan, Hui-zhen Ye, and Zhao-ran Liang. “[Application of Qi-benefiting and Blood-supplementing Chinese Medicines Combined with Ozone in Radiotherapy of Nasopharyngeal Cancer].” International Journal of Triditional Chinese Medicine 31, no. 6 (2009): 558-559. 

Zhang, Li, Jia-kai Li, Zhao-hui Chen, Xi-jun Sun, and Jian-ping Liu. “[CT-guided intradiscal ozone injection combined with intervertebral facet joint steroid injection for lumbar disk herniation accompanied with intervertebral arthritis].” Journal of Interventional Radiology 18, no. 11 (2009): 853-855. 

Zhang, Ya-feng, Jian-wei Wang, Jian-ping Cai, Xiao-wu Tian, and Hua-wei Zou. “[Intradiscal Injection of Ozone for Treatment of Lumbar Disc Herniation].” Journal of Liaoning College of Traditional Chinese Medicine, no. 3 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-LZXB201003068.htm. 

Zhang, Ting-Jie, Yi Feng, Jun Li, Jin-Jun Yang, and Zhi-Fang Zhong. “[Percutaneous ozone chemonucleolysis combined with radiofrequency thermocoagulation for treatment of cervical disc herniation].” Chinese Journal of Pain Medicine, no. 4 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZTYZ201004010.htm. 

Zhang, Zhicai, Jinde Li, and Haibin Luo. “[CT-guided Ozone Injection for Lumbar Intervertebral Disc Protrusion].” Chinese Journal of Minimally Invasive Surgery, no. 9 (2010). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZWWK201009016.htm. 

Zhang, Hong-xin, Zhi-min Wang, Xin-ming Ma, Shi-xin Chen, Jian-ming Peng, Wu-ping Zhang, Xue-jiang Qian, et al. “[Intradiscal injection of ozone combined with epidural injection of collagenase for the treatment of prominent lumbar disc protrusion:a multicentral application observation].” Journal of Interventional Radiology 19, no. 3 (2010): 201-204. 

Zhao, Zhengqi. “[Therapeutic effect of coblation nucleoplasty combined with O_2-O_3 mixture injection within and outside intervertebral disc on lumbar disc herniation].” Hebei Medical Journal, no. 14 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HBYZ200914013.htm. 

Zhao, Wei, Xiao-feng He, Yi-kai Xu, and Wei-zhong Wang. “[The value of high intensity zone in diagnosing lumbar annular disruption before lumbar intradiscal ozone injection].” Journal of Interventional Radiology, no. 3 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200703010.htm. 

Zhao, Qing, Huiliang Yang, Xuanbo Ning, and Jiang Yue. “[Clinical Research on Ozone Injected by CT Targeting Treatment for Lubar Intervertebral Disc Protrusion].” China Modern Doctor, no. 7 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZDYS200807010.htm. 

Zhao, Wei, Wei-zhong Wang, Xiao-feng He, Ying Chen, Ke-xiu Duan, Ming Yi, Yan Zneg, and Yu-yan Wang. “[Study on correlation between the pressure of lumbar ozone-injection and damage of the lumbar anulus fibrosus].” Journal of Interventional Radiology, no. 10 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200810017.htm. 

Zhao, Bo, Gao-Hai Shao, Yu Yu, Yong-Fa Zhou, Bin Zhong, and Chao He. “[Preliminary report for treatment of discogenic low back pain with combined percutaneous laser and O2-O3 mixture].” Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology 21, no. 5 (May 2008): 391-392. 

Zhao, Hui, Wei Chai, Wei Gao, Lixian Xu, Hui Zhang, and Yonghui Yang. “Hyperoxygenated solution: effects on acute hypobaric hypoxia-induced oxidative damage in rabbits.” High Altitude Medicine & Biology 10, no. 3 (2009): 283-291. 

Zhao, Nian, Chun-hua Li, and De-xiu Li. “[Intradiscal and Paraspinal Injection of Oxygen-ozone in the Treatment of Lumbar Disc Herniation].” Radiologic Practice 6, no. 10 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-FSXS200906034.htm. 

Zhao, Zi-jian, Yu-cai Zou, Meng-zhang Liu, Ai-xia Li, and Hong-wei Lin. “[Clinical Study of the treatment of cervical spondylosts with percutaneous laser disc decompression combined with ozone injecaon].” Chinese Journal of Primary Medicine and Pharmacy 16, no. 2 (2009): 241-242. 

Zhao, Xiaodong, Zhirui Yuan, Meiqi Fu, Dazhi Xie, Yaowu Long, Chaozuo Li, and Feng Wang. “[Percutaneous laser disc decompression combined with ozone nucleus gelatinosus oxidizing technique for cervical intervertebral disc protrusion].” International Medicine & Health Guidance News 16, no. 16 (2010): 1962-1965. 

Zheng, Zhao-jian. “Clinical observation on Ashi point injection of ozone for tennis elbow.” Journal of Acupuncture and Tuina Science 7, no. 6 (2009): 347-348. 

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Zhou, Ling, Ai-lin Luo, and Rong-chun Li. “[Clinical Efficacy of Oxygen-ozone Therapy for Lumbar Intervertebral Disc Herniation].” Journal of Clinical Research 12, no. 2 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-HNYZ200802026.htm. 

Zhou, Nai-bao, Zhi-jian Fu, and Tao Sun. “[Effects of ozone on rat astrocytes in vitro].” Journal of Shandong University (Health Sciences), no. 9 (2008): 863-865. 

Zhou, Nai-bao, Zhi-jian Fu, and Tao Sun. “Effects of different concentrations of oxygen-ozone on rats' astrocytes in vitro.” Neuroscience Letters 441, no. 2 (August 22, 2008): 178-182. 

Zhou, Lingjun, Ziliang Qiang, Zuo Gu, Xiaolei Zhang, Yangya Quan, and Yong Li. “[Efficacy of low-temperature plasma nucleus ablation with ozone injection for lumbar intervertebral disc herniation].” Pain Clinic Journal, no. 2 (2009): 89-93. 

Zhou, Fang, Qing-Shan Zhou, Rong-Chun Li, Long Wang, Ling Zhou, and Ding-Yu Zhang. “[Clinical efficacy of oxygen-ozone therapy for lumbar disc herniation combined with lumbar spinal stenosis].” Chinese Journal of Pain Medicine 15, no. 4 (2009): 203-205. 

Zhou, Weihong, Weibing Liu, Xiaobing Wang, Yuan Wen, and Xiaokun Hu. “[CT-Guided Percutaneous Ablation Ozone Discectomy for Treating Cervical Lumbar Disc Herniation].” Beijing Biomedical Engineering 28, no. 2 (2009): 206-209. 

Zhou, Bin, Hai-yan Zhou, Pei-hua Xu, Hong-mei Wang, Xian-ming Lin, and Xuan-ding Wang. “Hyperoxygenated solution for improved oxygen supply in patients undergoing lung lavage for pulmonary alveolar proteinosis.” Chinese Medical Journal 122, no. 15 (August 5, 2009): 1780-1783. 

Zhu, Hong-qian, Dong-lin Xiong, and Jin Jiang. “[Clinical therapeutic effect of percutaneous laser disc decompression and ozone injected at the target on lumbar intervertebral disc herniation under the guidance of digital subtraction angiography].” Pain Clinic Journal, no. 3 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-TTXZ200803009.htm. 

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Zou, Yucai, Zijian Zhao, Mengzhang Liu, Aixia Li, Biao Jiang, and Hongwei Lin. “[Treatment of prolapse of lumbar intervertebral disc with percutaneous laser disc decompression combined with ozone intervention].” China Journal of Modern Medicine, no. 20 (2009). http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZXDY200920027.htm. 

Zuo, Jin-liang, Xin-wei Zhu, and Qi Pan. “[Spinal dural injury of rabbits by medical ozone].” Journal of Cervicodynia and Lumbodynia, no. 3 (2008). http://en.cnki.com.cn/Article_en/CJFDTOTAL-JYTZ200803008.htm. 

“[The Evaluation of Curative Effect in the Therapy of Lumbar Disc Herniation with Medical Ozone].” Journal of Practical Radiology, no. 9 (2007). http://en.cnki.com.cn/Article_en/CJFDTOTAL-SYFS200709050.htm. 

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